A mixture of 4 different variants of esterified testosterone in a certain proportion is best known under the name of Sustanon 250 (developed and manufactured by Organon). It contains:
30 mg Testosterone propionate,
60 mg testosterone
60 mg of testosterone Isocaproate
100 mg testosterone decanoate
The idea of combining all these different testosterone esters is to provide drug based on testosterone, which will provide the user immediate effects due to rapid release of testosterone propionate ester followed by a slower and more sustained release of other esters. A further advantage is that the mixture does not require such frequent administration such as testosterone propionate. Sustanon 250 as a whole is designed to provide a maximum plasma testosterone levels after 24 to 48 hours after administration. After this time, the plasma testosterone levels increase for 21 days because of the longer-esterified testosterone in the mixture. Sustanon 250 is most likely one of the most popular testosterone preparations. Mainly because of misconceptions that Sustanon 250 is more effective than individual esterified forms of testosterone, which is not true. Esters linked to different anabolic steroids only affect the biological half-life and the release half-life, regardless of the anabolic steroid, to which they are attached. The real and the main reason for its popularity among athletes is quite a large volume of the substance for the money. A mixture of four different testosterone esters have a great value for money compared to buying individual testosterone esters.
The mixture of testosterone is subject to the effects of the enzyme aromatase in the body .Among the side effects of Sustanon-250 are side effects of estrogen. The rate of aromatization is directly related to the amount of used substance, and together with increasing doses aromatization is higher. Estrogenic side effects include: excessive water retention and bloating, elevated blood pressure (e.g. due to water retention in the body), accelerated fat deposition and gynecomastia. The side effects of estrogen can be reduced or completely avoided by using aromatase inhibitors or SERMs (selective estrogen receptor modulators. Among androgenic side effects are: increased secretion of sebum (oily skin), acne (in terms of increased secretion of sebum), body hair growth, and increased risk of inducing male pattern baldness (MPB) in persons with a genetic predisposition.
Anabolic / androgenic steroids can have deleterious effects on blood cholesterol levels. This includes a tendency to reduce HDL (good) cholesterol and increase LDL (bad) cholesterol.
All anabolic steroids have the ability to suppress or shut down the natural endogenous production of testosterone in the body, and Sustanon 250 is no exception.After the end of the cycle, it is highly recommended to use a suitable PCT (Post Cycle Therapy).
Beginners are using doses ranging from 300 to 500 mg per week, which is the standard dose for a beginner with any other testosterone cures. This dose should produce dramatic increases even at the lower end of the dosage. Intermediate users will generally make much progress at doses of 500-750 mg per week. Advanced users will make great progress at the same dosage as intermediate users, and rarely need to rise above this amount. In any case, advanced users tend to use Sustanon 250 ranging from 500 to 1000 mg per week. Detection time of Sustanon-250 is due to containing long esters at least 120 days.