Anastrozole (Arimidex) 1mg by Dragon Pharma — Complete Guide
Dragon Pharma Oral / Ancillary 100 tabs × 1mg ⭐ Aromatase Inhibitor (AI)
Manufacturer: Dragon Pharma
Substance: Anastrozole (Arimidex)
Package: 100 tabs × 1mg
Substance: Anastrozole (Arimidex)
Package: 100 tabs × 1mg
Half-life: 46-50 hours
Bioavailability: 85%
Peak plasma: 2 hours
Bioavailability: 85%
Peak plasma: 2 hours
What is Anastrozole (Arimidex)?
Anastrozole (brand name Arimidex) is a non-steroidal aromatase inhibitor (AI) used to control estrogen levels during anabolic steroid cycles. First approved by the FDA in 1995 for breast cancer treatment, it has become a cornerstone in bodybuilding for preventing estrogenic side effects including gynecomastia, water retention, and high blood pressure.
Unlike SERMs (tamoxifen, clomiphene) which block estrogen receptors, Anastrozole reduces estrogen production by inhibiting the aromatase enzyme — the same enzyme that converts androgens (testosterone) into estrogen.
⚙️ How Does Anastrozole Work?
Anastrozole is a highly selective non-steroidal aromatase inhibitor that works by:
- ⬇ Inhibiting aromatase enzyme — Prevents conversion of androgens to estrogen
- ⬇ Reducing serum estradiol (E2) — Lowers circulating estrogen levels by 70-80%
- ⬆ Increasing testosterone availability — Less estrogen conversion means more free testosterone
- Non-suicidal (reversible) — Enzyme function returns after drug clearance
✅ Key fact: Anastrozole does NOT completely eliminate estrogen — it maintains E2 levels within physiological range when dosed correctly. Estrogen is still necessary for joint health, mood, libido, and cardiovascular function.
Anastrozole 1mg — Dosage Protocols
| Cycle Aromatization | Example Compounds | Anastrozole Dose | Frequency |
|---|---|---|---|
| Low | Primobolan, Anavar, Winstrol, Masteron | 0.25-0.5mg | Every 3-4 days (as needed) |
| Moderate | Testosterone (300-500mg/week), Turinabol | 0.5mg | Every other day (EOD) |
| High | Testosterone (500-750mg/week), Dianabol, Anadrol | 0.5-1mg | Every other day (EOD) |
| Very High | Testosterone (750-1000mg/week) + Dianabol | 1mg | Every day or EOD |
Important: Always start with the lowest effective dose. Blood work (estradiol sensitive test) is the only accurate way to dial in your AI dosage. Target E2 range: 20-40 pg/mL.
Signs You Need Anastrozole (High Estrogen)
Physical signs
Water retention / bloating, puffy face, itchy / sensitive nipples, gynecomastia (lumps)
Water retention / bloating, puffy face, itchy / sensitive nipples, gynecomastia (lumps)
Psychological signs
Mood swings, increased anxiety, lethargy, poor sense of well-being
Mood swings, increased anxiety, lethargy, poor sense of well-being
Blood pressure signs
Elevated BP (above 130/85), frequent headaches, nosebleeds
Elevated BP (above 130/85), frequent headaches, nosebleeds
⚠️ Signs of LOW Estrogen (Crashing E2 — Anastrozole Overdose)
⚠️ Crashing estrogen is worse than high estrogen! Signs include:
- Dry, painful, cracking joints
- Complete loss of libido / erectile dysfunction
- Depression, anxiety, emotional flatness
- Extreme fatigue, no motivation
- Hot flashes and night sweats
- Insomnia despite being tired
Solution: Skip the next Anastrozole dose and reduce frequency by 50%. E2 will recover within 7-10 days.
Anastrozole vs Other AIs — Comparison
| AI | Type | Half-life | Estrogen suppression | Best for |
|---|---|---|---|---|
| Anastrozole (Arimidex) | Non-suicidal (reversible) | 46-50 hours | 70-80% | On-cycle estrogen control |
| Exemestane (Aromasin) | Suicidal (irreversible) | 24 hours | 85% | PCT, no estrogen rebound |
| Letrozole (Femara) | Non-suicidal (reversible) | 48 hours | 90-95% | Severe gyno reversal (aggressive) |
Anastrozole in Cycle Protocols
Testosterone Only (500mg/week)
Start Anastrozole 0.5mg EOD. Adjust based on blood work (E2 target: 20-40).
Start Anastrozole 0.5mg EOD. Adjust based on blood work (E2 target: 20-40).
Testosterone + Dianabol
Start Anastrozole 0.5-1mg EOD. Monitor E2 and blood pressure closely.
Start Anastrozole 0.5-1mg EOD. Monitor E2 and blood pressure closely.
TRT (100-200mg/week)
Most men don’t need AI. If needed: 0.25mg 2x/week.
Most men don’t need AI. If needed: 0.25mg 2x/week.
Contraindications & Precautions
- Do not use Anastrozole without an aromatizing androgen (testosterone or Dianabol)
- Avoid in women who are pregnant, breastfeeding, or may become pregnant
- Use with caution in individuals with osteoporosis (estrogen is bone-protective)
- Not recommended for long-term TRT without blood work confirmation
❓ Frequently Asked Questions
What is the standard dosage of Anastrozole 1mg?
0.5-1mg every other day (EOD). For moderate cycles: 0.5mg EOD. For high aromatizing cycles: 1mg EOD. Always start low and adjust based on blood work and symptoms.
When should I take Anastrozole during a cycle?
Start at the beginning of the cycle — prevention is easier than treating gynecomastia. Starting dose for 500mg Testosterone: 0.5mg EOD.
Can I crash my estrogen with Anastrozole?
Yes. Low estrogen symptoms include dry joints, low libido, erectile dysfunction, fatigue, depression, and poor well-being. Dose adjustment is critical. Skip next dose and reduce frequency.
What is the difference between Anastrozole and Aromasin?
Anastrozole is non-suicidal (reversible, better for on-cycle), Aromasin is suicidal (irreversible, may be preferred for PCT to avoid estrogen rebound).
Can women take Anastrozole?
Generally not recommended for healthy women. Anastrozole is used in women with hormone-sensitive breast cancer under medical supervision only.
How many tablets are in one Dragon Pharma package?
100 tablets of 1mg each.
What is the half-life of Anastrozole?
Approximately 46-50 hours, allowing for every-other-day (EOD) or every-3-day dosing.
Medical Disclaimer: This information is for educational purposes only. Anastrozole is a potent prescription aromatase inhibitor with significant side effects if misused. Estrogen management should be guided by regular blood work (estradiol sensitive test). Consult a qualified physician before use.
