Manufacturer: Wyeth
Category: Fat Loss Pills
Substance: Sibutramine Hydrochloride
Package: 10 pills

Out of stock

Sibutramine active principle of Sibus, Biomag, Redulip, Saciette, Sibutram, Sigran, Slenfig, Vazy, Nolipo, Meridia, Reductil reduce calorie intake by inhibiting appetite and increase satiety and raises metabolism, increasing the body’s calorie consumption.
Sibutramine acts in the hypothalamus (in the brain) which is responsible for anxiety control and hunger. So is classified as Moderator of appetite being administered orally for the treatment of obesity.  Recommended for weight loss and maintenance of weight lost.

In 2011, the United Kingdom made an extensive review of the medical literature and analyzed studies, with a minimum duration of 1 year, which treated obese patients with weight loss diet associated with the medicine Sibutramine (Sibus, Biomag, Redulip, Saciette, Sibutram, Sigran, Slenfig, Vazy, Nolipo, Meridia, Reductil).

In the studies reviewed, associate Sibutramine (Sibus, Biomag, Redulip, Saciette, Sibutram, Sigran, Slenfig, Vazy, Nolipo, Meridia, Reductil) to a low-calorie diet showed weight loss, gradual and constant, during one year (duration of treatment).

Statistically significant beneficial effects were found in levels of HDL cholesterol and triglycerides.
Bythe other hand, was an increase in diastolic blood pressure levels.
Sibutramine is contraindicated in cases of:
  • Hypertension is not sufficiently controlled.
  • Psychiatric conditions as bulimia nervosa, anorexia nervosa, depression, or preexisting mania.
  • Hypersensitivity to the drug
  • Patients below 18 years of age.
  • Concomitant treatment with monoamine Oxidase inhibitors (MAO), antidepressants or other centrally active drugs.
  • Pulmonary hypertension.
  • Existing lesions in heart valves, coronary heart disease, congestive heart failure, serious arrhythmia and myocardial infarction.
  • Stroke or transient ischemic attack.
  • Hyperthyroidism.
  • Closed angle Glaucoma.
  • Seizure problems.
  • Enlargement of the prostate gland with urinary retention.
  • Pheochromocytoma.
  • Pregnant or lactating women.

The most common side effects are:

  • dry mouth
  • Paradoxically high appetite
  • nausea
  • strange taste in the mouth
  • irritated stomach
  • constipation
  • trouble sleeping
  • dizziness
  • menstrual pain
  • headache
  • drowsiness
  • pain in muscles and joints.

In some patients sibutramine can raise blood pressure. In this way, all treated with sibutramine should go through regular monitoring of the pressure.

The following side effects are uncommon but serious and require immediate medical attention: cardiac arrhythmia, paresthesia, mental and mood changes.

Symptoms that require urgent medical attention are: seizure, problem urinating, chest pain, hemiplegia, abnormal vision, Dyspnea and edema.