Tamoxifen 40mg is a hormonal drug that is an antagonist of estrogen. Once in the human body, its active component binds to a specific receptor and prevents the absorption of them of estrogen. Thus, Tamoxifen slows the growth of estrogen-dependent tumors. Besides, it has effects similar to estrogen, positively affecting the state of the endometrium of the uterus, musculoskeletal, cholesterol levels in the blood.
Prescribe Tamoxifen 40mg at estrogen-dependent tumors, breast cancer, uterine cancer, melanomas, carcinomas of the prostate, sarcomas and some other types of tumors. Also, this drug can be used for hormone replacement therapy after removal of the ovaries or in the absence of ovulation.
Produce Tamoxifen 40mg in pill form. Manual of drug reports that is first assigned to a smaller dose, which, after some time, increased to the required. The basic principle of the dosing Tamoxifen is the individual selection.
Not recommended treatment Tamoxifen people with individual intolerance, severe deficiencies of hematopoiesis. Diabetes, ophthalmic disorders, also should be cause for special caution during therapy with this medication. Separately, it should be noted that women in childbearing age, up until menopause, you should apply severe birth-control measures without the use of hormonal contraceptive drugs. Threat to pregnancy are a period of treatment with Tamoksifenom and two months after its completion. Also, at this time should refrain from breastfeeding an infant.
Side effects and overdose Tamoxifen 40mg.
The annotation of the medication provided that the number of adverse effects from Tamoxifen is less than that of the hormonal drugs which also are used in the treatment of cancer. However, the described effects such as hot flashes, heat, bleeding, itching – they are due to antiestrogen effect of the drug. Can occur the common adverse effects – dyspepsia, edema, hair loss, and so on. The basic rule for correction Tamoxifen therapy accompanied by side effects, is decrease the dose. This drug should be accompanied by medical and laboratory control. Cases of overdose not described, but it is assumed the manifestation of the action similar to the action of estrogen. Measures should be taken symptomatic.